Låner fra tekinvestor ettersom jeg ikke sant noe konkret om dette her.


chunwaitsui15
7
346
28 juni
Arbeidet Dr Konstantin Kloppstech VP Technology LIFECARE (DD/LC) har utført.

Power point: https://simuleurope.com/2018/attd/Files/(andreas.pfuetzner@pfuetzner-mainz.com)ePoster%20NIA.pdf 11

Presentasjonen beskriver hvor mye mer nøyaktig deres nanosensor er kontra enzyme-linked immunosorbent assay (ELISA). Ser at linken ikke fungerer ved å trykke direkte på den så klipp og lim hele adressen.

The ELISA reference method was shown to have a 100 % specificity within an observed linear detection range from 10 ng/mL to 1000 ng/mL With similar specificity, the linear detection range of the NIA was shown to be between 0.01 ng/mL to 1 ng/mL, i.e. the NIA was 1000fold more sensitive than the reference ELISA. Minor unspecific binding of IgG was observed with the NIA technology at chicken IgG concentrations > 1000 ng/mL

“ELISAs are one of the most sensitive immunoassays available. The typical detection range for an ELISA is 0.1 to 1 fmole or 0.01 ng to 0.1 ng”
Forklaring om Elisa deteksjon: https://www.enzolifesciences.com/science-center/technotes/2019/september/why-are-sensitivity-and-specificity-important-parameters-for-an-elisa?/ 1

Her står det altså “the NIA was 1000 fold more sensitive than the reference ELISA”

NIA:
NANO-IMMUNO-ASSAY (NIA) - A CANTILEVER-BASED
NANOSENSOR TECHNOLOGY FOR POINT-OF-CARE
MEASUREMENT OF PROTEINS IN BIOLOGICAL SAMPLES

In our proof-of-concept experiment, the NIA in comparison to the classic ELISA was shown to be substantially more sensitive, less time and resource consuming. With the NIA it is possible to determine the analyte-binding directly within minutes and without any further labeling requirement. In addition, the small size of the NIA sensors allows for integration into Lab-on-a-Chip technologies, which will enable point-of-care testing with a laboratory
quality level.